Overview of Inactivated Poliovirus Vaccine
Polio is a highly infectious viral disease that primarily affects children under the age of five. The virus spreads through contaminated water and food, and it can lead to permanent paralysis or even death. India has made significant strides in eradicating polio, and vaccination plays a crucial role in maintaining this status.

What is the Inactivated Poliovirus Vaccine, who should receive it, and what is its schedule?
The Inactivated Poliovirus Vaccine (IPV) is derived from killed poliovirus and is used to protect against polio. It is administered via injection and is part of the routine immunization schedule in India.
Vaccination Schedule:
- Birth dose: Oral Polio Vaccine (OPV) at birth
- Primary series: IPV at 6 and 14 weeks of age (fractional doses)
- Booster dose: At 16-24 months of age
For those who missed the initial doses, IPV can still be administered up to the age of 5 years
Who should avoid the Inactivated Poliovirus Vaccine?
Certain individuals should not receive the IPV vaccine due to potential complications. This includes those who:
- Have had a severe allergic reaction to a previous dose of the vaccine or any of its components (e.g., streptomycin, polymyxin B, neomycin)
- Have a serious illness at the time of vaccination (vaccination can be postponed until recovery).
What changes occur after Inactivated Poliovirus vaccination?
Following IPV vaccination, some common side effects may occur, including:
- Redness, swelling, or soreness at the injection site
- Fever
- Fatigue
These side effects are usually mild and resolve within a few days.
How safe is the Inactivated Poliovirus Vaccine?
The IPV vaccine is generally safe and effective. It provides long-term protection against polio, significantly reducing the risk of paralysis and other severe complications. Serious side effects are rare.
While the IPV vaccine is safe, you should consult your doctor if you experience any of the following:
- Persistent pain or swelling at the injection site
- Severe allergic reaction (e.g., difficulty breathing, swelling of the face and throat)
- High fever
Cost of Inactivated Poliovirus Vaccine?
IPV vaccines range from approximately ₹700 to ₹2,495 per dose, depending on the composition, manufacturer, and healthcare facility.
When to see a doctor?
After receiving the IPV vaccine, you should consult a doctor if you experience any of the following:
- Severe allergic reactions: Symptoms like difficulty breathing, swelling of the face or throat, or hives.
- High fever: A fever that persists or is unusually high.
- Unusual behavior: Signs of confusion or extreme irritability.
- Persistent pain or swelling: At the injection site that doesn’t improve.
- Muscle weakness: Any signs of muscle weakness or paralysis.
These symptoms are rare, but it’s important to seek medical advice if they occur. For most people, the vaccine is safe and side effects are mild