Overview of Pentavalent Vaccination
The Pentavalent vaccine is a combination vaccine that protects against five serious diseases: Diphtheria, Pertussis (whooping cough), Tetanus, Hepatitis B, and Haemophilus influenzae type B (Hib). This vaccine is a crucial part of India’s Universal Immunization Programme, aimed at reducing the incidence of these life-threatening diseases in children.

What is the Pentavalent vaccine, who should receive it, and what is its schedule?
The Pentavalent vaccine is administered as an intramuscular injection. It is typically given to all infants at 6, 10, and 14 weeks of age. This schedule ensures that children receive early protection against these five diseases. Booster doses for DTP (Diphtheria, Tetanus, and Pertussis) are recommended at 16-24 months and 5 years of age.
Who should avoid the Pentavalent vaccine?
Certain individuals should not receive the Pentavalent vaccine due to potential complications. This includes those who:
- Have had a severe allergic reaction to a previous dose of the vaccine.
- Have a known severe allergy to any component of the vaccine.
- Are suffering from a moderate or severe illness at the time of vaccination (they should wait until they recover).
What changes occur after Pentavalent vaccination?
After receiving the Pentavalent vaccine, some children may experience mild side effects such as:
- Fever
- Redness or swelling at the injection site
- Irritability
These side effects are generally mild and resolve on their own. Serious side effects are rare but can include severe allergic reactions.
How safe is the Pentavalent vaccine?
The Pentavalent vaccine is generally safe and well-tolerated. It has been extensively tested and monitored for safety. The benefits of vaccination far outweigh the risks, as it provides protection against five potentially deadly diseases.
Cost of Pentavalent Vaccine?
The Pentavalent vaccine is provided free of charge under the Universal Immunization Programme in India. In private healthcare settings, the cost can vary but is generally around ₹500-₹1,000 per dose.
When to see a doctor?
While the Pentavalent vaccine is safe, you should consult a healthcare provider if you notice any of the following:
- Severe allergic reactions such as difficulty breathing, swelling of the face or throat, or hives.
- High fever or unusual behavior.
- Persistent crying or seizures.