Overview of Japanese encephalitis (JE) Vaccine
Japanese encephalitis (JE) is a mosquito-borne viral infection that affects the brain. It is a significant health concern in many parts of Asia, including India. The virus is primarily transmitted by the Culex mosquito, which breeds in rice paddies and other standing water sources. JE can cause severe neurological damage and even death, particularly in children.

What is the Japanese encephalitis (JE) vaccine, who should receive it, and what is its schedule?
The Measles-Rubella (MR) vaccine is a combined vaccine that protects against both measles and rubella. It is part of the routine The Japanese Encephalitis vaccine is used to protect against JE infection. It is derived from an inactivated virus and is included in India’s Universal Immunization Programme (UIP). The vaccination schedule generally includes:
- First dose: At 9 months of age, along with the measles vaccine.
- Second dose: At 16-24 months of age, along with the DPT booster
For adults and older children who are at risk, the vaccine can also be administered. The adult JE vaccination is particularly recommended in areas with high JE incidence.
Who should avoid the Japanese encephalitis (JE) vaccine?
Certain individuals should not receive the JE vaccine due to potential complications. This includes those who:
- Have had a severe allergic reaction to a previous dose of the vaccine or any of its components.
- Are pregnant, unless the risk of JE infection is high.
- Have a serious illness at the time of vaccination (vaccination can be postponed until recovery)
What changes occur after Japanese encephalitis (JE) vaccination?
Following JE vaccination, some common side effects may occur, including:
- Pain, redness, or swelling at the injection site.
- Fever, headache, or muscle ache.
These side effects are usually mild and resolve within a few days.
How safe is the Japanese encephalitis (JE) vaccine?
The JE vaccine is generally safe and effective. It provides long-term protection against JE infection, significantly reducing the risk of severe neurological diseases. Serious side effects are rare.
While the JE vaccine is safe, you should consult your doctor if you experience any of the following:
- Persistent pain or swelling at the injection site.
- Severe allergic reaction (e.g., difficulty breathing, swelling of the face and throat).
- High Fever.
Cost of Japanese encephalitis (JE) Vaccine?
The cost of JE vaccines in India can vary. For example, the JENVAC vaccine is priced around ₹70 per dose. Prices may vary depending on the healthcare facility and the specific vaccine used.
When to see a doctor
After receiving the JE vaccine, you should consult a doctor if you experience any of the following:
- Unusual behavior: Signs of confusion or extreme irritability
- Severe allergic reactions: Symptoms like difficulty breathing, swelling of the face or throat, or hives
- High fever: A fever that persists or is unusually high.
- Persistent pain or swelling: At the injection site that doesn’t improve.
- Muscle weakness: Any signs of muscle weakness or paralysis.
These symptoms are rare, but it’s important to seek medical advice if they occur. For most people, the vaccine is safe and side effects are mild.